What is fibrin?

Fibrin is a fully autologous material, similar to platelet-rich plasma. Fibrin is obtained by slower centrifugation of blood samples, compared to platelet-rich plasma. It does not contain substances that inhibit blood clotting and contains the protein fibrinogen, which forms a reticular structure – fibrin – when it comes into contact with tissues. It promotes tissue regeneration and rejuvenation processes, as the retention time of growth factors in the skin is much longer than after plasma administration (scientific data speak of up to 14 days).

Additional components by which fibrin differs from plasma:

  • the presence of CD34+ stem cells
  • presence of a small number of leukocytes
  • presence of fibrinogen


Biorevolumetry – is it possible?

Obtaining a long-lasting effect as after fillers is not possible because fibrin is an absorbable material (much faster than, for example, cross-linked hyaluronic acid). However, it is possible to observe the effects of improved skin volume and quality, noticeable by the patient. This seems to be related to a longer stimulation of collagen synthesis than with platelet-rich plasma.