Micro-puncture and micro-needle mesotherapy treatments are among the methods of regenerative medicine.

The latest micro-puncture device (version 4) is an improvement on the original device that has been in production for several years.

Mechanism of action:

  • Initiation of a cascade of damage-regeneration processes in the epidermis and skin. Microneedling leads to the secretion of platelet-derived growth factor (PGF), TGF-alpha and beta, connective tissue growth factor and FGF (fibroblast growth factor – responsible for the production of collagen)
  • increased production of type I, III, VII collagen and elastin
  • thickening of the basal layer of the epidermis (containing living cells of the epidermis)
  • neovascularisation – improvement of skin vascularisation

Certified preparations are administered during the treatment and are designed to be combined with micro-puncture treatment – i.e. micro-needle mesotherapy.
Micro-needle mesotherapy is designed to: increase the effects of the treatment, improve healing, introduce rejuvenating and healing substances into the epidermis and skin.

Dermapen can be used in all skin phototypes, the risk of hyper or hypopigmentation is much lower than with energy-based devices (IPLs, older types of micro-needle radiofrequency devices)

Collagen production continues for 3 – 6 months after treatment, the effects are long-lasting.



  • skin rejuvenation, wrinkles
  • photoageing
  • enlarged pores
  • all types of scars, including acne and burn scars
  • post-inflammatory acne discolouration
  • melasma
  • eyelid hyperpigmentation
  • stretch marks
  • rosacea, vascular skin



  • reduction of wrinkles
  • reduction of pores
  • reduction of scars
  • reduction of stretch marks
  • glowing skin
  • baby face effect
  • reduction of hyperpigmentation
  • inhibition and reversal of the ageing process
  • hydrating and nourishing the skin


  • a series of 3-5 treatments every 3-6 weeks
  • after the treatment the patient applies soothing preparations and a filter cream to mask redness and is prepared to go outside
  • gentle skin care is recommended in the following days, make-up can be applied